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PYA 11100
Product Information Molecular Structure

3-(2'-Deoxy-β-D-2-ribofuranosyl)pyrido[2,3-d]
pyrimidine-2,7(8H)-dione

Notes: Fluorescent deoxycytidine analog.

Description:  Download a brief overview here. Known as "dF" or "P". Ribo version fluoresces at 385 nm (Bergstrom, D. E.; Inoue, H.; Reddy, P. A., J. Org. Chem., 1982, 47, 2174-2178; Bergstrom, D., et. Al, Synlett, 1992, 179-188). Has been incorporated into oligonucleotides, where dF pairs with dG, resulting in a higher melting temperature (Inoue, H.; Imura, A.; Ohtsuka, E., Nucleic Acids Res., 1985, 13, 7119-7128). In triple helices, dF pairs well with dA (Staubli, A. B.; Dervan, P. B., Nucleic Acids Res. 1994, 22, 2637-2642). We also offer the phosphoramidite version (Product # BA 0238, CAS Reg. No. 162585-09-3), which has been used for oligonucleotide synthesis (Durland, R. H.; Rao, T. S.; Jayaraman, K.; Revankar, G. R., Bioconjugate Chem., 1995, 6, 278-282), where it is known as "P", and serves as a fluorescent replacement of T in targeting AT base pairs during triplex formation.

3-(2'-Deoxy-β-D-2-ribofuranosyl)pyrido[2,3-<em>d</em>]pyrimidine-2,7(8<em>H</em>)-dione
Product Details Product Pricing

MF: C12H13N3O5

MW: 279.25

CAS NO: 99517-98-3

Storage Conditions: 5 oC

Purity≥95%

Availability: 

Stock maintained. Ships within 1-3 days.

Alternate Name: 

"dF" or "P"
Unit Weight Unit Price Quantity
10 mg $105.00
100 mg $245.50
1 g $1,495.00
 
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