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BA 0346
Product Information Molecular Structure

5-(2-Furyl)-dU CEP

Notes: Small, fluorescent natural base mimic that can signal the presence of abasic sites in hybridized DNA oligonucleotides.

Description: 

BA 0346 is a phosphoramidite of a small, fluorescent nucleoside that is an isosteric mimic of thymidine.1,2 This probe has been shown to pair with adenine to form a stable duplex. DNA probes constructed to contain BA 0346 at a selected sequence position show a significant emission enhancement when hybridization results in an opposing abasic residue as compared to an opposing adenine residue.1 This property makes BA 0346 useful for the preparation of probes that are designed to detect sequence-specific depurination and depyrimidination.

For more information, download a Product Information Sheet for BA 0346 here.

1) Greco, N.J.; Tor, Y. J. Am. Chem. Soc. 2005, 127, 10784-10785.

2) Greco, N.J.; Tor, Y. Nature Protocols, 2007, 2, 305-316.

5-(2-Furyl)-dU CEP
Product Details Product Pricing

MF: C43H49N4O9P

MW: 796.86

CAS NO: 863713-51-3

Storage Conditions: Dry, -20 C

Purity≥95%

Availability: 

Stock maintained. Ships within 1-3 days.

Alternate Name: 

5-Furan-2-yl dU CEP
Unit Weight Unit Price Quantity
100 µmol $245.00
0.25 g $580.00
 
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