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BA 0279
Product Information Molecular Structure

2-Fluoro-I CEP

Notes: The convertible nucleoside 2-Fluoro-I CEP allows the formation of N2-alkyl-G residues in RNA for structural studies.

Description:  After incorporation of this unit into an oligoribonucleotide by standard phosphoramidite chemistry, treatment with ammonia, methylamine, or a higher alkylamine, including one bearing a tethered functional group, leads to displacement of fluoride ion with resultant installation of a 2-amino group, i.e., producing a guanosine or an N2-alkyl-G residue. Download Product Information.

Allerson, C. R.; Chen, S. L.; Verdine, G. L. J. Am. Chem. Soc. 1997, 119, 7423-7433.

2-Fluoro-I CEP
Product Details Product Pricing

MF: C54H67FN7O10PSi

MW: 1052.22

CAS NO: 220382-27-4

Storage Conditions: -20 oC, dry

Purity≥95%

Availability: 

Stock maintained. Ships within 1-3 days.

Alternate Name: 

3'-O-[(Diisopropylamino)(2-cyanoethoxy)phosphino]-5'-
O-(4,4'-dimethoxytrityl)-2-fluoro-6-O-(4-
nitrophenylethyl)-2'-O-(tert-butyldimethylsilyl)
inosine

Alternate Name: 

Convertible G CEP or NPE-FI CEP
Unit Weight Unit Price Quantity
50 µmol $275.00
0.25 g $975.00
 
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