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Full Catalog (page 19)
Product Number Product Name Molecular Formula Cas. No.

PR 3465

2'-Deoxyisoguanosine

C10H13N5O4 

106449-56-3 

Description

The transposition of atoms or groups in the purine nucleobase of G/dG provides isomers that have altered base-pairing capabilities.We offer a family of guanosine isomers in nucleoside and phosphoramidite forms.

Isoguanosines are important in the field of non-natural base pairing. In 1989, Benner and co-workers1 reported the enzymatic incorporation of iso-G into RNA and DNA and characterized the distinct non-natural base pairing that resulted, especially pairing involving the similarly transposed isomer of dC known as iso-dC (we offer the closely-related compound 5-Methyliso-dC, PY 7255

Iso-G and Iso-dG are part of a family that includes Guanosine (PR 3703) , 2'-Deoxyguanosine (PR 3452) , the isomeric nucleosides 2'-Deoxypseudoguanosine (Pseudo-dG, PRA 10103) , 2'-Deoxypseudoisoguanosine (Pseudoiso-dG, PRA 10104) and the phosphoramidites Pseudo-dG CEP (BA 0312) and Pseudoiso-dG CEP (BA 0314)

Learn more about these novel compounds and their use by downloading a Product Information sheet for our family of guanosine isomers

1. Switzer, C. Y.; Moroney, S. E.; Benner, S. A. J. Am. Chem. Soc. 1989, 111, 8322-8323.

Notes

Isoguanosine (Iso-G, PR 3735) and 2'-Deoxyisoguanosine (Iso-dG, PR 3465) are isomeric with G/dG, differing by transposition of the carbonyl group at position 6 of G or dG with the C-NH2 group at position 2, providing a novel hydrogen bond donor/acceptor pattern.

Alternate Name(s):

Iso-dG

2-Oxo-2'-deoxyadenosine

PR 3470

2'-Deoxynebularine

C10H12N4O3 

4546-68-3 

PR 3480

3',5'-Di-O-acetyl-2'-
deoxyinosine

C14H16N4O6 

106568-79-0 

PR 3490

3',5'-Di-O-acetyl-O6-phenyl-
2'-deoxyinosine

C20H20N4O6 

133471-06-4 

PR 3495

2',3'-Dideoxyadenosine

C10H13N5O2 

4097-22-7 

PR 3496

2-Fluoro-2'-deoxyadenosine

C10H12FN5O3 

21679-12-9 

PR 3500

2',5'-Dideoxy-8,5'-cycloadenosine

C10H11N5O2 

275821-04-0 

PR 3505

2'-3'-Dideoxyguanosine

C10H13N5O3 

85326-06-3 

Description

For multi-gram quantities, please inquire.

PR 3510

N6-(Diisobutylaminomethylidene)
-2'-deoxyisoguanosine

C19H30N6O4 

207981-31-5 

PR 3520

N6-(Diisobutylaminomethylidene)
-5'-O-(dimethoxytrityl)-O2-
(diphenylcarbamoyl)-2'-
deoxyisoguanosine

C53H57N7O7 

207981-37-1 

PR 3530

N6-(Diisobutylaminomethylidene)
-O2-(diphenylcarbamoyl)-2'-
deoxyisoguanosine

C32H39N7O5 

207981-34-8 

PR 3540

2',3'-Di-O-
methyladenosine

C12H17N5O4 

20649-46-1 

PR 3590

5'-O-(Dimethoxytrityl)-N2-
(dimethylaminomethylidene)-3'-
deoxyguanosine

C34H36N6O6 

172361-60-3 

PR 3600

5'-O-(Dimethoxytrityl)-N2-
ethyl-2'-deoxyguanosine

C33H35N5O6 

337380-92-4 

PR 3605

3',5'-Di-O-acetyl-2'-
deoxyguanosine

C14H17N5O6 

69992-10-5 

PR 3610

5'-O-(Dimethoxytrityl)-8-Oxo-
N2-isobutyryl-2'-
deoxyguanosine

C35H37N5O8 

136859-77-3 

Description

Inquire about pricing on 10 g (800-357-1145).

For the phosphoramidite, see BA 0010 .

Alternate Name(s):

5'-O-(Dimethoxytrityl)-8-hydroxy-N2-isobutyryl-2'-deoxyguanosine

PR 3630

5'-O-(Dimethoxytrityl)-N2-
methyl-2'-deoxy-guanosine

C32H33N5O6 

869354-96-1 

PR 3640

5'-O-(Dimethoxytrityl)-2'-O-
methylinosine

C32H32N4O7 

128219-84-1 

PR 3660

5'-O-(Dimethoxytrityl)-O6-
phenyl-2'-deoxyinosine

C37H34N4O6 

133471-08-6 

PR 3670

2-(Dimethylaminomethylidene)amino-
6-methoxylamino-9-(β-D-2-
deoxyribofuranosyl)purine

C14H21N7O4 

869354-99-4 

PR 3680

2-(Dimethylaminomethylidene)amino-
9-(β-D-2-deoxyribofuranosyl)
purine

C13H18N6O3 

869355-02-2 

PR 3690

N2-(Dimethylaminomethylidene)-
3'-deoxyguanosine

C13H18N6O4 

869355-04-4 

PR 3692

2,6-Bis-O-[2-(4-nitrophenyl)
ethyl]-2'-deoxyxanthosine

C26H26N6O9 

123107-74-4 

PR 3700

N2-Ethyl-2'-
deoxyguanosine

C12H17N5O4 

101803-03-6 

Description

DNA guanine nucleobases are effectively ethylated by acetaldehyde, the primary oxidative metabolite of ethanol. For a leading reference, please see Vaca, C.E., et. Al., Carcinogenesis, 1995, 16, 2177-2185.

Notes

PR 3700 is the N-ethyl analog of guanosine.

PR 3701

5'-O-Dimethoxytrityl-N2-
(trifluoroacetamido)hexyl-2'-
deoxyguanosine

C39H43F3N6O7 

None Assigned 

PR 3702

N2-
Dimethylguanosine

C12H17N5O5 

2140-67-2 



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