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Full Catalog (page 18)
Product Number Product Name Molecular Formula Cas. No.

PR 3300

8-Bromo-2'-deoxyguanosine

C10H12BrN5O4 

13389-03-2 

PR 3310

8-Bromo-5'-O-(dimethyoxytrityl)-
N2-(dimethyl-aminomethylidene)-
2'-deoxyguanosine

C34H35BrN6O6 

204582-53-6 

PR 3320

8-Bromo-N6-
(dimethylaminomethylidene)-2'-
deoxyadenosine

C13H17BrN6O3 

207906-52-3 

PR 3330

8-Bromo-N2-
(dimethylaminomethylidene)-2'-
deoxyguanosine

C13H17BrN6O4 

717876-75-0 

PR 3335

5'-O-Dimethoxytrityl-N2-
(dimethylaminomethylidene)-8-
ethenyl-2'-deoxyguanosine

C36H38N6O6 

1101864-07-6 

Description

Versatile vinyl substituted synthetic intermediate for the preparation of a variety of photochromic nucleosides (PCNs).1,2

1. Ogasawara, S.; Saito, I.; Maeda, M. Tet. Lett., 2008, 49, 2479-82.

2. Ogasawara, S.; Maeda, M. Angew. Chem. Int. Ed., 2008, 47, 8839-42.

PR 3340

8-Bromo-5'-O-(dimethoxytrityl)-
N6-(dimethylaminomethylidene)-
2'-deoxyadenosine

C34H35BrN6O5 

207906-53-4 

PR 3350

3'-O-(t-Butyldimethylsilyl)-5'-
oxo-2'-deoxy-8,5'-cycloadenosine

C16H23N5O3Si 

None Assigned 

PR 3360

5'-Chloro-5'-deoxyadenosine

C10H12ClN5O3 

892-48-8 

PR 3370

6-Chloro-9-(β-D-2-
deoxyribofuranosyl)purine

C10H11ClN4O3 

4594-45-0 

PR 3380

6-Chloro-9-(3,5-O-di-(p-
toluoyl)-β-D-2-deoxyribofuranosyl)
purine

C26H23ClN4O5 

91713-46-1 

Description

Useful synthon for preparation of 6-substituted purine 2'-deoxyribosides.

PR 3390

6-Chloro-9-(5-O-dimethoxytrityl-
β-D-2-deoxyribofuranosyl)
purine

C31H29ClN4O5 

133931-96-1 

Description

THIS PRODUCT HAS BEEN DISCONTINUED

PR 3400

6-Chloro-9-(β-D-ribofuranosyl)
purine

C10H11ClN4O4 

5399-87-1 

PR 3410

(5'S)-8,5'-Cycloadenosine

C10H11N5O4 

41432-67-1 

PR 3420

(5'S)-2'-Deoxy-8,5'-
cycloadenosine

C10H11N5O3 

117182-88-4 

PR 3430

3'-Deoxyadenosine

C10H13N5O3 

73-03-0 

Alternate Name(s):

Cordycepin

PR 3440

5'-Deoxy-8,5'-cycloadenosine

C10H11N5O3 

3415-89-2 

PR 3445

2'-Deoxyadenosine Monohydrate

C10H13N5O3 

16373-93-6 

PR 3450

2'-Deoxy-4-desmethylwyosine

C13H15N5O4 

101803-00-3 

Description

A convenient synthon for the preparation on N-2-alkyl derivatives of 2'-deoxyguanosine: Ueda, T, et al., Nucleosides & Nucleotides, 1985, 4, 595-606.

PR 3452

2'-Deoxyguanosine monohydrate

C10H13N5O4.H2O 

312693-72-4 and 961-07-9 (anhydrous) 

PR 3455

α-2'-Deoxyguanosine

C10H13N5O4 

19916-78-0 

PR 3460

3'-Deoxyguanosine

C10H13N5O4 

3608-58-0 

PR 3463

2'-Deoxyinosine

C10H12N4O4 

890-38-0 

PR 3464

5'-Azido-2',5'-dideoxyinosine

C10H11N7O3 

496809-83-7 

PR 3465

2'-Deoxyisoguanosine

C10H13N5O4 

106449-56-3 

Description

The transposition of atoms or groups in the purine nucleobase of G/dG provides isomers that have altered base-pairing capabilities.We offer a family of guanosine isomers in nucleoside and phosphoramidite forms.

Isoguanosines are important in the field of non-natural base pairing. In 1989, Benner and co-workers1 reported the enzymatic incorporation of iso-G into RNA and DNA and characterized the distinct non-natural base pairing that resulted, especially pairing involving the similarly transposed isomer of dC known as iso-dC (we offer the closely-related compound 5-Methyliso-dC, PY 7255

Iso-G and Iso-dG are part of a family that includes Guanosine (PR 3703) , 2'-Deoxyguanosine (PR 3452) , the isomeric nucleosides 2'-Deoxypseudoguanosine (Pseudo-dG, PRA 10103) , 2'-Deoxypseudoisoguanosine (Pseudoiso-dG, PRA 10104) and the phosphoramidites Pseudo-dG CEP (BA 0312) and Pseudoiso-dG CEP (BA 0314)

Learn more about these novel compounds and their use by downloading a Product Information sheet for our family of guanosine isomers

1. Switzer, C. Y.; Moroney, S. E.; Benner, S. A. J. Am. Chem. Soc. 1989, 111, 8322-8323.

Notes

Isoguanosine (Iso-G, PR 3735) and 2'-Deoxyisoguanosine (Iso-dG, PR 3465) are isomeric with G/dG, differing by transposition of the carbonyl group at position 6 of G or dG with the C-NH2 group at position 2, providing a novel hydrogen bond donor/acceptor pattern.

Alternate Name(s):

Iso-dG

2-Oxo-2'-deoxyadenosine

PR 3470

2'-Deoxynebularine

C10H12N4O3 

4546-68-3 

PR 3480

3',5'-Di-O-acetyl-2'-
deoxyinosine

C14H16N4O6 

106568-79-0 



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