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Full Catalog (page 12)
Product Number Product Name Molecular Formula Cas. No.

FC 8160

Tocopherol-TEG azide

C37H65N3O5 

None Assigend 

Description

For a complete listing of our reagents for click chemistry, please see our Click-matesTM Collection page.

The purchase of these products for use in applications relating to copper catalyzed azide-alkyne cycloaddition chemistry (“Click Chemistry”) includes a limited, nontransferable license to intellectual property owned by TSRI to use this product solely for internal non-commercial research activities and specifically excludes clinical, therapeutic, or diagnostic use in humans or animals. Information regarding a license for commercial use in Click Chemistry may be obtained directly from The Scripps Research Institute, 10550 N. Torrey Pines Rd., La Jolla, CA 92037, or by contacting 858-784-8140 or click@scripps.edu.

Notes

Lipophilic carrier tag from our Click-matesTM collection.

FC 8170

PQQ-TEG azide

C22H22N6O11 

1333145-23-5 

Description

For a complete listing of our reagents for click chemistry, please see our Click-matesTM Collection page.

PQQ-TEG azide is covered under US patent #8,198,290 B2, Berry & Associates, Inc.

The purchase of these products for use in applications relating to copper catalyzed azide-alkyne cycloaddition chemistry (“Click Chemistry”) includes a limited, nontransferable license to intellectual property owned by TSRI to use this product solely for internal non-commercial research activities and specifically excludes clinical, therapeutic, or diagnostic use in humans or animals. Information regarding a license for commercial use in Click Chemistry may be obtained directly from The Scripps Research Institute, 10550 N. Torrey Pines Rd., La Jolla, CA 92037, or by contacting 858-784-8140 or click@scripps.edu.

Notes

Useful azide from our Click-matesTM collection for the installation of a methoxatin tag.

Alternate Name(s):

Methoxatin-TEG azide

Pyrroloquinolinequinone 7-((11-azido-3,6,9-trioxaundecyl)oxy)amide

FC 8180

Cholesteryl-TEG azide

C36H62N4O5 

None Assigned 

Description

For a complete listing of our reagents for click chemistry, please see our Click-matesTM Collection page.

The purchase of these products for use in applications relating to copper catalyzed azide-alkyne cycloaddition chemistry (“Click Chemistry”) includes a limited, nontransferable license to intellectual property owned by TSRI to use this product solely for internal non-commercial research activities and specifically excludes clinical, therapeutic, or diagnostic use in humans or animals. Information regarding a license for commercial use in Click Chemistry may be obtained directly from The Scripps Research Institute, 10550 N. Torrey Pines Rd., La Jolla, CA 92037, or by contacting 858-784-8140 or click@scripps.edu.

Notes

Useful azide from our Click-matesTM collection for the installation of a cholesteryl tag.

FC 8190

DTPA-Quinolone-TEG azide

C33H47N9O14 : C3H6O6 

None Assigned 

Description

A number of luminescent probes wherein lanthanide ions are chelated to organic chromophores have been reported by Mustaev, et al.1-6 FC 8190 is our first product for this approach to luminescence.7 We now provide the organic molecule that lets you add the lanthanide of your choosing to complete the luminescent probe that best suits your needs. The design of FC 8190 incorporates three elements in a single organic molecule that sequesters lanthanide ions: (1) a diethylenetriaminepentaacetic acid (DPTA) fragment, which serves to chelate Lanthanides such as Eu+3 or Tb+3; (2) a quinolone chromophore, which serves as an antenna for ultraviolet light; and (3) a hydrophilic tether with a distal azide, which provides a site for conjugation to biomolecules via the click reaction. The luminescence exhibited by such organic lanthanide chelates makes them useful probes for investigating biological processes. The quinolone chromophore absorbs UV light and then transmits energy to the chelated lanthanide ion, which in turn emits discrete bands of visible light. The large Stokes shift, long luminescence lifetime and narrow emission bands that are observed provide the capability for highly sensitive detection.

References

1. Krasnoperov, L.N.; Marras, S.A.E.; Kozlov, M.; Wirpsza, L.; Mustaev, A. Bioconjugate Chem., 2010, 21, 319-327.

2. Mustaev, A.; Kozlov, M.; Marras, S.; Krasnoperov, L.; Wirpsza, L.; Pillai, S. PCT Int. Appl., 2011, WO 2011088193 A2.

3. Pillai, S.; Kozlov, M.; Marras, S.A.E.; Krasnoperov, L.N.; Mustaev, A. Prog. Nanotechnology and Nanomaterials, 2012, 1(1), 18-24.

4. Wirpsza, L.; Pillai, S.; Batish, M.; Marras, S.A.E.; Krasnoperov, L.; Mustaev, A. J. Photochemistry and Photobiology, B: Biology, 2012, 116, 22-29.

5. Pillai, S.; Kozlov, M.; Marras, S.A.E.; Krasnoperov, L.N.; Mustaev, A. J. Fluorescence, 2012, 22(4), 1021-1032.

6. a) Ge, P.; Selvin, P.R. Bioconjugate Chem. 2004, 15, 1088-1094; b) Li, M.; Selvin, P.R. Bioconjugate Chem. 1997, 8, 127-132.

7. Manufactured and sold under a license agreement with the University of Medicine and Dentistry of New Jersey.

Notes

This product has been discontinued

FC 8200

Azidocoumarin N-
hydroxysuccinimide ester

C15H10N4O7 

None Assigned 

Description

For additional information regarding azidocoumarins and cycloaddition reactions please see the following:

Sivakumar, K.; Xie, F.; Cash, B.M.; Long, S.; Barnhill, H.N.; Wang, Q. Org. Lett. 2004, 6, 4603-4606.

Notes

A profluorophore from our Click-mates TM collection which provides strong fluorescence upon cycloaddition with an alkyne.

FC 8205

Azidocoumarin-spacer-12-amine
formate

C18H23N5O8 

None Assigned 

Description

For additional information regarding azidocoumarins and cycloaddition reactions please see the following:

Sivakumar, K.; Xie, F.; Cash, B.M.; Long, S.; Barnhill, H.N.; Wang, Q. Org. Lett. 2004, 6, 4603-4606.

Notes

A profluorophore from our Click-mates TM collection which provides strong fluorescence upon cycloaddition with an alkyne.

FC 8210

Azidocoumarin-spacer-6-amine
formate

C14H15N5O6 

None Assigned 

Description

For additional information regarding azidocoumarins and cycloaddition reactions please see the following:

Sivakumar, K.; Xie, F.; Cash, B.M.; Long, S.; Barnhill, H.N.; Wang, Q. Org. Lett. 2004, 6, 4603-4606.

Notes

A profluorophore from our Click-mates TM collection which provides strong fluorescence upon cycloaddition with an alkyne.

FC 8215

Azidocoumarin-spacer-12-maleimide

C21H21N5O8 

None Assigned 

Description

For additional information regarding azidocoumarins and cycloaddition reactions please see the following:

Sivakumar, K.; Xie, F.; Cash, B.M.; Long, S.; Barnhill, H.N.; Wang, Q. Org. Lett. 2004, 6, 4603-4606.

Notes

A profluorophore from our Click-mates TM collection which provides strong fluorescence upon cycloaddition with an alkyne.

FC 8225

2-(4-(t-Butoxy)phenyl)
ethylamine

C12H19NO 

157981-64-1 

FC 8250

Cyanine 3 TEG azide

C36H49 BF4N6O4 

None Assigned 

FD 13001

Diazaindacene N-
hydroxysuccinimide ester

C21H21N3O6 

1027512-35-1 

Description

Lightner and co-workers1-3 reported the synthesis and spectroscopic properties of fluorophores based on the 3a,4a-diazaindacene ring system ("xanthglows"). Key properties include a high quantum yield (>0.9) and a large Stokes shift (>100 nm). Berry & Associates offers an amine-reactive version, Diazaindacene NHS Ester, for incorporation of the diazaindacene fluorophore into biomolecules.

Download Product Information.



Spectroscopic properties: The absorption maximum of the corresponding carboxylic acid is reported to be 425 nm in methanol, extinction coefficient = 15,300. The emission maximum of the carboxylic acid is 535 nm in methanol with a quantum yield of 0.91.1 When installed onto a 5'-amino-modified oligonucleotide,4 the absorption and emission maxima appear at 430 nm and 530 nm, respectively, in aqueous MgCl2/KCl/Tris-HCl (pH 8.0). For comparison, an analogous TET-labeled oligonucleotide showed absorption and emission maxima at 522 nm and 538 nm, respectively.

1. Brower, J. O.; Lightner, D. A. J. Org. Chem. 2002, 67, 2713-2716.

2. Boiadjiev, S. E.; Lightner, D. A. J. Phys. Org. Chem. 2004, 17, 675-679.

3. Woydziak, Z. R.; Boiadjiev, S. E.; Norona, W. S.; McDohagh, A. F.; Lightner, D. A. J. Org. Chem. 2005, 70, 8417-8423.

4. We thank Professor Salvatore A. E. Marras for these data.

Notes

A useful fluorophore exhibiting an emission maxiumum at 530-535 nm, a large Stokes shift, and a high quantum yield.

Alternate Name(s):

3a,4a-Diaza-4,5-dioxo-7-ethyl-3a,4,4a,5-tetrahydro-1,3,6-trimethyl-s-indacen-2-yl-acetic acid, N-hydroxysuccinimide ester

FD 13005

Water soluble dansyl-TEG azide

C23H34N5NaO8S2 

None Assigned 

Description

For a complete listing of our reagents for click chemistry, please see our Click-matesTM Collection page.

The purchase of these products for use in applications relating to copper catalyzed azide-alkyne cycloaddition chemistry (“Click Chemistry”) includes a limited, nontransferable license to intellectual property owned by TSRI to use this product solely for internal non-commercial research activities and specifically excludes clinical, therapeutic, or diagnostic use in humans or animals. Information regarding a license for commercial use in Click Chemistry may be obtained directly from The Scripps Research Institute, 10550 N. Torrey Pines Rd., La Jolla, CA 92037, or by contacting 858-784-8140 or click@scripps.edu.

Notes

Useful tool from our Click-matesTM collection for ligation of a water soluble dansyl group via Saudinger ligation or click chemistry.

Alternate Name(s):

4-Dansyl-(4-aza-7,10,13-trioxa-15-azido)pentadecylsulfonate

FF 6000

5-Carboxyfluorescein

C21H12O7 

76823-03-5 

FF 6010

6-Carboxyfluorescein

C21H12O7 

3301-79-9 

FF 6015

6-Carboxyfluorescein dipivalate

C31H28O9 

192374-17-7 

FF 6020

6-Carboxyfluorescein diacetate

C25H16O9 

3348-03-6 

FF 6030

5-Carboxyfluorescein diacetate

C25H16O9 

79955-27-4 

FF 6040

6-Carboxyfluorescein diacetate N-
Hydroxysuccinimide Ester

C29H19NO11 

150206-15-8 

FF 6050

5-Carboxyfluorescein diacetate N-
Hydroxysuccinimide Ester

C29H19NO11 

150206-05-6 

FF 6060

6-Carboxyfluorescein N-
Hydroxysuccinimide Ester

C25H15NO9 

92557-81-8 

FF 6070

5-Carboxyfluorescein N-
Hydroxysuccinimide Ester

C25H15NO9 

92557-80-7 

FF 6080

6-Carboxyfluorescein dipivalate
N-Hydroxysuccinimide
Ester

C35H31NO11 

197850-75-2 

FF 6090

5-Carboxyfluorescein dipivalate
N-Hydroxysuccinimide
Ester

C35H31NO11 

186032-65-5 

FF 6100

N-(6-Hydroxyhexyl)-6-
carboxamidofluorescein dipivalate

C37H14NO9 

467455-27-2 

FF 6110

6-Carboxyfluorescein-TEG azide

C29H28N4O9 

412319-45-0 

Description

For a complete listing of our reagents for click chemistry, please see our Click-matesTM Collection page.

The purchase of these products for use in applications relating to copper catalyzed azide-alkyne cycloaddition chemistry (“Click Chemistry”) includes a limited, nontransferable license to intellectual property owned by TSRI to use this product solely for internal non-commercial research activities and specifically excludes clinical, therapeutic, or diagnostic use in humans or animals. Information regarding a license for commercial use in Click Chemistry may be obtained directly from The Scripps Research Institute, 10550 N. Torrey Pines Rd., La Jolla, CA 92037, or by contacting 858-784-8140 or click@scripps.edu.

Notes

Useful fluorescein azide from our Click-matesTM collection for fluorescein incorporation via Staudinger ligation or click chemistry.

Alternate Name(s):

6-FAM-TEG azide

FF 6120

6-Carboxyfluorescein-dipivalate
TEG azide

C39H44N4O11 

1254709-11-9 

Description

For a complete listing of our reagents for click chemistry, please see our Click-matesTM Collection page.

The purchase of these products for use in applications relating to copper catalyzed azide-alkyne cycloaddition chemistry (“Click Chemistry”) includes a limited, nontransferable license to intellectual property owned by TSRI to use this product solely for internal non-commercial research activities and specifically excludes clinical, therapeutic, or diagnostic use in humans or animals. Information regarding a license for commercial use in Click Chemistry may be obtained directly from The Scripps Research Institute, 10550 N. Torrey Pines Rd., La Jolla, CA 92037, or by contacting 858-784-8140 or click@scripps.edu.

Notes

Useful fluorescein azide from our Click-matesTM collection for fluorescein incorporation via Staudinger ligation or click chemistry.

Alternate Name(s):

6-FAM-dipivalate-TEG azide



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