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Product Number | Product Name | Molecular Formula | Cas. No. |
D-(+)Biotin N-Hydroxysuccinimide |
C14H19N3O5S |
35013-72-0 |
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NotesBiotinylation reagent for labeling nucleic acids or proteins. |
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D-(+)Biotin 2-Nitrophenyl Ester |
C16H19N3O5S |
131303-71-4 |
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NotesBiotinylation reagent for labeling nucleic acids or proteins. |
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D-(+)-Biotin-tyramine amide |
C18H25N3O3S |
41994-02-9 |
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DescriptionD-(+)-Biotin-tyramine amide (BT 1015, also called biotinphenol) is used as a labeling probe for intracellular proteins in the proteomic mapping of the mitochondrial matrix.1 The tyramide functionality enables high density biotin labeling of nucleic acid sequences or proteins through the catalytic activity of horseradish peroxidase. This approach can provide increased sensitivity compared to traditional avidin-biotinylated enzyme complex approaches.2 1. Rhee, H.-W.; Zou, P.; Udeshi, N.D.; Martell, J.D.; Mootha, V.K.; Carr, S.A. Science, 2013, 339, 1328-1331. 2. a) Bobrow, M.N.; Harris, T.D.; Shaughnessy, K.J.; Litt, G.L. J. Immun. Methods 1989, 125, 279-285. b) Speel, E.J.M.; Hopman, A.N.H.; Komminoth, P.J. Histochem & Cytochem, 1999, 47, 281-288.Alternate Name(s):Biotin phenol |
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N-(16-(Dimethoxytrityl)oxy-15- |
C43H59N3O10S |
869354-57-4 |
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N-(15,16-Dihydroxy-4,7,10,13- |
C22H41N3O8S |
869354-59-6 |
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N1-(4-(t-Butyl)benzoyl)-D-(+) |
C27H31N3O6S |
869354-61-0 |
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N1-(Dimethoxytrityl)-D-(+) |
C37H37N3O7S |
869354-63-2 |
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D-Desthiobiotin |
C10H18N2O3 |
533-48-2 |
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DescriptionDesthiobiotin allows capture by streptavidin and can be displaced simply by adding biotin.1-3 For phosphoramidite and CPG versions, see BA 0210 and BA 0211. For the NHS ester of desthiobiotin, see BT 1070 .1. General: Hirsch, J.D.; Eslamizar, L.; Filanoski, B.J.; Malekzadeh, N.; Haughland, R.P.; Beechem, J. M.; Haughland, R.P. Anal. Biochem. 2002, 308, 343-357. 2. Key references on Desthiobiotin NHS Ester: (a) Hofmann, K.; Titus, G.; Montibeller, J.A.; Finn, F.M. Biochemistry, 1982, 21, 978-984. (b) Romovacek, H.; Finn, F.M.; Hofmann, K. Biochemistry, 1983, 22, 904-909. (c) Finn, F.M.; Titua, G.; Hofmann, K. Biochemistry, 1984, 23, 2554-2558. 3. Regarding association constants and kinetics: (a) Busse, S.; Scheumann, V.; Menges, B.; Mittler, S. Biosensors and Bioelectronics, 2002, 17, 704-710. (b) Yoon, H.C.; Hong, M.-Y.; Kim, H.-S. Langmuir, 2001, 17, 1234-1239. NotesFor affinity capture via the biotin-streotavidin interaction. |
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Desthiobiotin N- |
C14H21N3O5 |
80750-24-9 |
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DescriptionDesthiobiotin allows capture by streptavidin and can be displaced simply by adding biotin.1-3 For phosphoramidite and CPG versions, see BA 0210 and BA 0211. For desthiobiotin, see BT 1060 .1. General: Hirsch, J.D.; Eslamizar, L.; Filanoski, B.J.; Malekzadeh, N.; Haughland, R.P.; Beechem, J. M.; Haughland, R.P. Anal. Biochem. 2002, 308, 343-357. 2. Key references on Desthiobiotin NHS Ester: (a) Hofmann, K.; Titus, G.; Montibeller, J.A.; Finn, F.M. Biochemistry, 1982, 21, 978-984. (b) Romovacek, H.; Finn, F.M.; Hofmann, K. Biochemistry, 1983, 22, 904-909. (c) Finn, F.M.; Titua, G.; Hofmann, K. Biochemistry, 1984, 23, 2554-2558. 3. Regarding association constants and kinetics: (a) Busse, S.; Scheumann, V.; Menges, B.; Mittler, S. Biosensors and Bioelectronics, 2002, 17, 704-710. (b) Yoon, H.C.; Hong, M.-Y.; Kim, H.-S. Langmuir, 2001, 17, 1234-1239. NotesFor affinity capture via the biotin-streotavidin interaction. |
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Desthiobiotin-TEG azide |
C18H34N6O5 |
1306615-47-3 |
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DescriptionFor a complete listing of our reagents for click chemistry, please see our Click-matesTM Collection page. The purchase of these products for use in applications relating to copper catalyzed azide-alkyne cycloaddition chemistry (“Click Chemistry”) includes a limited, nontransferable license to intellectual property owned by TSRI to use this product solely for internal non-commercial research activities and specifically excludes clinical, therapeutic, or diagnostic use in humans or animals. Information regarding a license for commercial use in Click Chemistry may be obtained directly from The Scripps Research Institute, 10550 N. Torrey Pines Rd., La Jolla, CA 92037, or by contacting 858-784-8140 or click@scripps.edu.NotesA useful tool from our Click-matesTM collection for ligation of desthiobiotin via Saudinger ligation or click chemistry. |
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N1-(D-(+)-Biotinyl)-1,19- |
C24H46N4O7S |
869354-65-4 |
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Alternate Name(s):3-[[N-(D-(+)-Biotinyl)-3-aminopropoxy(ethoxy)ethoxy]-ethoxy-1-aminopropane |
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Biotin-TEG azide |
C18H32N6O5S |
875770-34-6 |
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DescriptionFor a complete listing of our reagents for click chemistry, please see our Click-matesTM Collection page. The purchase of these products for use in applications relating to copper catalyzed azide-alkyne cycloaddition chemistry (“Click Chemistry”) includes a limited, nontransferable license to intellectual property owned by TSRI to use this product solely for internal non-commercial research activities and specifically excludes clinical, therapeutic, or diagnostic use in humans or animals. Information regarding a license for commercial use in Click Chemistry may be obtained directly from The Scripps Research Institute, 10550 N. Torrey Pines Rd., La Jolla, CA 92037, or by contacting 858-784-8140 or click@scripps.edu.NotesA useful tool from our Click-matesTM collection for ligation of biotin via Saudinger ligation or click chemistry.Alternate Name(s):N-(11-Azido-3,6,9-trioxa-undecylamine)-D-(+)-biotinamide |
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Thiol cleavable biotin |
C22H42N4O4S3 |
1946010-72-5 |
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Alternate Name(s):Aminooxy-S-S-cleavable biotin |
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6-Chlorosalicylic acid |
C7H5ClO3 |
56961-31-0 |
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DescriptionTheherbicide Dicamba, 3,6-dichloro-2-methoxybenzoic acid, is biodegraded under anaerobic conditions, proceeding by demethylation to 3,6-dichlorosalicylic acid and reductive dechlorination to 6-chlorosalicylic acid. See: Taraban, R. H.; Berry, D. F.; Berry, D. A.; Walker, H. L, Jr. Applied and Environmental Microbiology, 1993, 59, 2332-2334. NotesBiodegredation product of the herbicide Dicamba.Alternate Name(s):2-Chloro-6-hydroxybenzoic acid |
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Protected U-U 5'-CEP |
C40H61N7O17P2Si |
915098-72-5 |
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1,4-Anhydro-2-deoxy-3,5-bis-O- |
C17H36O3Si2 |
173327-56-5 |
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DescriptionCR 2000 is a ribofuranoid glycal which has been cross-coupled with a variety of iodohetercycles to afford 2'-deoxy-C-nucleosides. For leading references, see: 1) Daves, G.D., Jr., Acc. Chem. Res. 1990, 23, 201-206; 2) Walker, J.A.; Chen, J.J; Hinkley, J.M.; Wise, D.S.; Townsend, L.B. Nucleosides & Nucleotides 1997, 16, 1999-2012; 3) Mayer, A.; Leumann, C.J. Nucleosides, Nucleotides & Nucleic Acids 2003, 22, 1919-1925; 4) Joubert, N.; Pohl, R.; Klepetarova, B.; Hocek, M. J. Org. Chem. 2007, 72, 6797-6805. |
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5-O-Benzoyl-1,2-di-O-acetyl-3- |
C16H18O7 |
4613-71-2 |
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NotesVorbruggen type ribosylation of an appropriate heterocycle with this sugar yields 3'-deoxynucleosides. |
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1-(α)-Chloro-3,5-di-O-p- |
C21H21O5Cl |
4330-21-6 or 3601-89-6 |
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NotesVersatile carbohydrate derivative universally used for the preparation of 2'-deoxy nucleosides. |
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3,5-Di-O-(t-Butyldimethylsilyl) |
C17H36O4Si2 |
83159-91-5 |
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1,2-Dideoxy-D-ribose (1,4-Anhydro- |
C5H10O3 |
91547-59-0 |
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1-Deoxy-D-ribose |
C5H10O4 |
51607-76-2 |
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Alternate Name(s):1,4-Anhydro-D-ribitol |
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5-O-(Dimethoxytrityl)-1,2- |
C26H28O5 |
95049-01-7 |
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1,3,5-Tri-O-benzoyl-2-O-methyl- |
C27H24O8 |
68045-07-8 |
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NotesVorbruggen ribosylation of appropriate heterocycles with this suger yields 2'-O-methynucleosides. |
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1,3,5-Tri-O-benzoyl-2-O-methyl- |
C27H24O8 |
632367-79-4 |
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DescriptionThis product has been discontinued |
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2,3,5-Tri-O-benzoyl-β-D- |
C26H21N3O7 |
7408-41-5 |
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2,3,5-Tri-O-benzoyl-β-D- |
C27H21NO7 |
23316-67-8 |
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NotesPrecursor to a large variety of C-nucleosides. |